4 anti-aging approaches revealed in 2025 that may help Americans live longer

Vitamin D3 supplementation can reduce biological wear and tear equivalent to nearly three years of aging, research has shown.(iStock)

Three months later, researchers at Harvard confirmed this correlation with their own study published in the same journal.

Daily vitamin D3 supplementation was found to prevent the shortening of telomeres, the protective ends on chromosome strands, which is a hallmark of aging.

2.Meditation practices may boost longevity

An April 2025 study by Maharishi International University (MIU), the University of Siegen, and the Uniformed Services University of the Health Sciences found thattranscendental meditationcan significantly alleviate stress and slow down aging.

The long-term meditation practice involves silently repeating a mantra in your head to achieve deep relaxation.

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The study, published in the journal Biomolecules, found that participants who practiced transcendental meditation had lower expression of the genes associated with inflammation and aging.

“These results support other studies indicating that thetranscendental meditation techniquecan reverse or remove long-lasting effects of stress,�“Lasting effects of stress are now recognized as causing or contributing to all diseases and disorders.”

Those who practiced transcendental mediation had a lower expression of genes associated with aging.(iStock)

3.GLP-1s are linked to reduction in mortality

A September 2025 study discovered that GLP-1 drugs, which are designed for diabetes andweight loss, could significantly reduce mortality for Americans.

Researchers at Swiss Re, a reinsurance company in Zurich, Switzerland, estimated that GLP-1 drugs could lead to a 6.4% reduction in all-cause mortality in the U.S.by 2045.In the U.K., more than a 5% reduction in mortality was projected over the same 20 years.

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slow cellular aging.

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A September 2025 study discovered that GLP-1 drugs could significantly reduce mortality for Americans.(iStock)

Researchers at Cornell University explored thelong-term benefitsof social connections on biological aging.

Social connection is a major player in extending longevity, research has shown.(iStock)

A similar study was published the same month, revealing thatcreative activitiessuch as music, dance, painting and even certain video games may help keep the brain biologically younger.

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Researchers from 13 countries — including teams at Trinity College Dublin in Ireland and SWPS University in Poland — analyzed brain data from more than 1,400 adults of all ages worldwide.Those who regularly pursued creative hobbies had brain patterns that appeared younger than their actual age.

Even short bursts of creative activity, such as a few weeks of strategy-based video gaming, had noticeable benefits.

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�s Deirdre Bardolf and Melissa Rudy contributed reporting.